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A laboratory to measure asbestos in the lungs (French)
Installed at Saint-Joseph-Saint-Luc Hospital, the mineralogyology laboratory has been operational since January.
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Truncating a Disease
The Reduction of Silica Hazards to Silicosis at the 1930 International Labor Office Conference on Silicosis in Johannesburg.
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Silicosis and scouring powder (French)
Of the 6 observations, the four patients who had a fatal outcome all breathed almost pure silica, 3 in the context of exposure to the scouring powder, only one during the handling of "silica flour" in foundry.
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Acute fatal silicosis by voluntary inhalation of scouring powder (French)
Acute silicosis was described in 1929 by Middleton in workers working in scouring plants. Symptoms occur two and a half to four years after the onset of exposure.
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Silico connectivity. About 3 cases of Caplan-Colinet syndrome (French)
RA is the most common inflammatory rheumatism affecting between 0.25 and 0.50% of the population and for 2/3 of women.
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Sarcoidosis and inorganic dust exposure in the MINASARC (Mineralo-Nano-SARCoidosis) study
It has been suggested that sarcoidosis may be associated with exposure to inorganic particles (Newman 2012, Vincent 2015). The mineral exposome can be studied by means of a specific questionnaire "whole life", in the professional and nonprofessional contexts and by mineralogical analysis carried out on the bronchoalveolar lavages (LBA). The MINASARC study is a prospective case-control study measuring mineral exposure Continue Reading
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Sarcoidosis or granulomatous reaction to metal overload: about three cases (French)
One of the causes of sarcoidosis could be an inorganic stimulus. Silica and talc have been incriminated but exposures to metals are more rare.
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Sarcoidosis and pulmonary dust: Mineralogical analysis (AM) in optical microscopy (OM) (French)
The entity of sarcoidosis or Besnier-Boeck-Schaumann disease was formed between 1888 and 1915 to lead to the concept of a systemic granulomatous disease mainly affecting the lung and the lymphatic system whose cause remains unknown for about a century .
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Sarcoidosis and pulmonary dust (French)
Since the description of two cases of silicosis by inhalation of Ajax, our team has been interested in the estimation of macrophagic dustiness in silica or silicate.
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Health: asbestos research is growing in Lyon (French)
The mineralogyology laboratory, based at the Saint-Joseph Saint-Luc hospital, extends to the Lyon Est medical school to learn more about inflammatory lung diseases.
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Clinical pneumology review (French)
Analysis of asbestos bodies and naked fibers in the pulmonary parenchyma of operated lung cancers.
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Redesigning the Workmen’s Compensation Regime (French)
Since 1996, every year, the branch of industrial accidents and occupational diseases of the Social Security has to pay several hundreds of millions of euros to the sickness branch of the general scheme, to compensate the expenses that it unduly supports.
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Reduction of under reporting of occupational lung cancer by lung tissue light mineralogic analysis associated to standardized questionnaire
In France recognition of OLC is considered as insufficient. Moreover some asbestos or other inorganic dust exposure may be related to an environmental factor.
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Dust and Health Day Program 2018 (French)
The "Third National Mineral Dusts and Health Day", organized on the occasion of the 30th anniversary of the ALCTMP, will take place on November 17, 2018 at the Jean Bosco Center (Lyon).
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Polishing of metal surgical parts, granulomatosis and mineralogical analysis (French)
When in the presence of granulomatosis, sometimes with necrosis, the bacterial research is negative, the diagnosis of sarcoidosis is evoked but the cause of this pathology is still unknown.
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Pulmonary and asbestos diseases (French)
Despite the ban on asbestos in France in 1996, the number of lung diseases related to exposure to asbestos is constantly increasing.
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Hiring research engineer (French)
Hiring a Young Researcher Profile Research Engineer.
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Laser Spectroscopy for in situ elemental imaging of lung issue:a promising technology
Environmental and occupational exposures to inhaled mineral particles, metals, and dust are major health problems. Pathologists infrequently report the presence of metals in tissues. Some respiratory diseases such as interstitial lung diseases (ILDs) might even be considered “idiopathic” by lack of complementary investigations regarding to the elemental composition.
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Lung tissue light microscopy analysis of inorganic fibrous and non fibrous minerals on 29 control patients obtained from Lyon’s Forensic Institute
Microscopic techniques for analyzing asbestos fibers in lung tissue have provided information in the understanding of asbestos-related diseases, and about mineral dust in lung tissue.
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The double punishment of asbestos cancer patients
How can we consider consolidated a cancer of the pleura that evolves?
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Interest of pulmonary Mineralogical Analysis (AM) in Infiltrative Syndromes (SI) (French)
The mineralogical analysis (AM) carried out from pulmonary biopsy (BP) and bronchio-alveolar lavage (LBA) makes it possible to highlight overloads in asbestos bodies (CA).
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In situ analysis by SEM-EDX spectroscopy of 10 sarcoidosis cases from MINASARC study
MINASARC is a case-control study (20 cases and 20 healthy volunteers) designed to assess the inorganic “exposome” by a specific questionnaire concomitantly with the mineralogical analysis (MA) of Broncho-Alveolar Lavage (BAL) fluid by transmission electron microscopy (TEM). One of the secondary objectives of this study is to compare those results with an in situ analysis of some paraffin embedded biopsies Continue Reading
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Identification of the location and chemical nature of mineral particles in patients with infiltrative pathology by mineralogical analysis (MA) of paraffin-embedded tissue biopsies using scanning electron microscopy (SEM) (French)
The histopathological observation of histological sections by optical microscopy (OM) in natural or polarized light makes it possible to highlight the presence of opaque or anisotropic particles and fibers without being able to determine their chemical nature. Our objective is to correlate this optical observation with a mineralogical study by scanning electron microscopy (SEM) coupled with X-ray emission analysis on Continue Reading
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From the Definition of Silicosis at the 1930 Johannesburg Conference to the Blurred Boundaries Between Pneumoconioses, Sarcoidosis, and Pulmonary Alveolar Proteinosis (PAP)
Since the twentieth century, the leading causes of illness have been attributed to nutritional deficiencies, to exposure to toxic substances and infectious agents, to psychological dysfunction, and/or to genetic predisposition.
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From the 1930 International Johannesburg Conference on Silicosis, to “Tables” of Occupational Diseases, France, 2000 Onward : A Comparative Reading
This article offers a comparative analysis of the proceedings of the 1930 International Labour Office (ILO) Conference on silicosis held in Johannesburg (designated “J30”) and of the French “tables” of occupational diseases1 (TODs) related to exposure to crystalline silica and silicates in the 2000s (designated “F2000”).
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Connective tissue disease due to intentional inhalation of scouring powder
In 1989, we examined a 20 year old woman with acute silicosis due to inhalation of scouring powder.
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Contribution of mineralogical analysis in thoracic oncology (French)
The article by Morelle et al reports the Belgian experience of identifying occupational exposures in thoracic oncology. It demonstrates once again the importance of under-reporting occupational diseases of these cancers and, consequently, claims for compensation.
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Cutaneous talc application and sarcoidosis (French)
We repport two sarcoidosis cases with diffuse nodes and a questionnaire showing frequent talc applications on iritated skin.
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Mineralogical analysis by electron microscopy and Laser Induced Breakdown Spectroscopy (LIBS) in two patients with sarcoidosis from the MINASARC study (French)
The MINASARC study is a case-control study (20 cases of sarcoidosis and 20 healthy volunteers) designed to evaluate the inorganic "exposome" by a occupational and environmental questionnaire concomitant with mineralogical analysis (AM) on bronchoalveolar lavage ( LBA) in transmission electron microscopy (MET) and biopsies embedded in paraffin by light microscopy (OM) and scanning electron microscopy (SEM). This study showed that Continue Reading
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Mineralogical analysis of BAL of healthy subjects by automatic detection of particles. Interest of their use as a control group in the context of the demonstration of a professional or environmental exposure. (French)
The difficulty of accessing a comprehensive retrospective knowledge of the occupational and environmental exposure of a patient invites the clinician to equip himself with various tools that can reinforce the anamnesis. It is thus relevant to resort to a directed interrogation of the patient and to a mineralogical analysis of the samples.
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An experiment in medicine, history, and the social sciences
This special issue of the American Journal of Industrial Medicine looks back to the International Conference on silicosis that took place in Johannesburg 85 years ago.
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2014_Catinon et al _Wire brushing wood furniture – SVDLD
Wire brushing wood furniture, granulomatosis and microscopic mineralogical analysis.
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